Terpenoids in Hemp: Beta-Caryophyllene

There are many components when it comes to hemp. Knowing all the types of terpenoids can be tricky but knowing that they fall into the phytochemical class. It can be responsible for the plants smell and even be used for medicine. This article will mainly focus on Beta-caryophyllene and exactly what it does to our body. Beta-caryophyllene is a type of terpenoid known as a sesquiterpenoid. When being extracted they use a heated method that can promote decarboxylation of certain components.

Beta-caryophyllene has been researched for its anti-inflammatory properties, even at low doses.

When we are in pain as humans there is usually a type of swelling or pain that is usually noticed when there are signs of inflammation. When we have an over stimulation of inflammation or even have it for long period of time it can cause the body great damage by deteriorating certain tissues.

In a study done on mice when given Beta-caryophyllene for their colon inflammation it was reduced significantly and prevented further damage with weight loss.Levels of interleukin-6, which is just another way that our body produces inflammation naturally was seen the be reduced by 55% when consuming beta-caryophyllene.

Perhaps the most interesting property of beta-caryophyllene, however, may be its demonstration as a stimulant of the cannabinoid-2 (CB2) receptors

From the endocannabinoid system it is known that the beta-caryophyllene can influence and bind to the CB2 receptor. When doing so it was shown to assist in balancing out many of the body’s normal functions such as movement, inflammation control, and immunity functions. The immune system is where the main CB2 receptors can be found so consuming enough beta-caryophyllene will ensure that your body can maintain healing itself and have less sick days.

Also no worry if you are ever concerned with the psychoactive part of this terpenoids there is no way that it can make you high or impair your judgement. It can only give benefit as an anti-inflammatory agent.

The anti-inflammatory effects of beta-caryophyllene may have contributed to hemp once being a popular treatment for duodenal ulcers.

Helping to protect the lining of the organs it can be seen to play a significant part when it comes to protecting the tissue from further damages. When women suffer from their monthly menstrual cycles it can be excruciating but when having essential oils blends containing beta-caryophyllene it helps to reduce their symptoms and be able to on as normal.

Another study done on mice was shown that even though  cannabidiol CBD can be seen as the main anti-inflammatory agent it can be seen that high-CBD whole extract was a more potent anti-inflammatory than CBD alone.

In summary we can see that the beta-caryophyllene plays an important part when it comes to hemp extract acting as an anti-inflammatory agent. More trials still need to be conducted to ensure that the effects of Hemp oils are really the answer to solving most of our every day discomforts.


1: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165946/

2: http://www.ncbi.nlm.nih.gov/pubmed/17188718/

3: Tortora, GJ & Derrickson, B, 2012, Principles of Anatomy & Physiology, 13th edn, Wiley.

4: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241751/

5: http://www.ncbi.nlm.nih.gov/pubmed/19704783/

6: http://www.ncbi.nlm.nih.gov/pubmed/17556587/

7: http://www.ncbi.nlm.nih.gov/pubmed/20251793/

8: https://www.researchgate.net/profile/Ming-Chiu_Ou/publication/221902096_Pain_relief_assessment_by_aromatic_essential_oil_massage_on_outpatients_with_primary_dysmenorrhea_A_randomized_double-blind_clinical_trial/links/0c9605298191b82f60000000.pdf

9: http://www.scirp.org/journal/PaperInformation.aspx?paperID=53912